10 Oct 08

Early achievement of a 1:1 ratio of FFP:PRBC reduces mortality in patients receiving massive transfusion

Posted in Transfusion medicine, Trauma at 18:13 by Laci

By E A Gonzalez, J jastrow, J B Holcomb, L S Kao, F A Moore, R A Kozar

J Trauma 2008;64:247

We previously demonstrated that uncorrected coagulopathy in patients receiving massive transfusion was associated with increased mortality. Based on these findings we implemented early goal directed therapy beginning at the time of injury to approach an optimal plasma:PRBC ratio of 1:1. The aim of the current study was to evaluate mortality after implementation of this practice.

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